Reprogramming cardiac health at the molecular level.
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Reprogramming cardiac health at the molecular level.
Learn MoreNexCardia™ is pioneering a new era in cardiac medicine, leveraging advanced biomolecular therapies to restore heart function and improve quality of life. Our flagship therapeutic, Diastelle™, reprograms the heart’s extracellular matrix and optimizes cardiomyocyte relaxation—supported by preclinical studies from the world’s top scientists in molecular cardiology, demonstrating significant reductions in fibrosis and marked gains in diastolic compliance.
Diastelle™ precisely modulates titin isoforms to enhance sarcomeric elasticity and promote cellular resilience in failing hearts.
Human cardiac organoid models confirm Diastelle™’s ability to improve relaxation kinetics by up to 40%, validating target engagement.
Diastelle™ uses activated polylaminin to re-educate the cardiac microenvironment— enhancing cardiomyocyte performance, reversing fibrosis, and restoring compliance to improve heart function.